Pituitary tumour types in dogs and cats

Pituitary tumours are common in dogs and being increasingly recognized cats. usually classified as adenomas should only be carcinomas when there is evidence of metastatic spread the tumour, which rare. Despite benign nature most pituitary tumours, they can still compress or invade neighbouring tissues. functional (hormonally active) non-functional silent). The aim this review was to provide an overview different tumour types cats that have been reported literature. In dogs, type corticotroph adenoma, cause pituitary-dependent hypercortisolism. cats, somatotroph hypersomatotropism, second-most adenoma. A lactotroph adenoma has described one dog, while gonadotroph, thyrotroph null cell not Hormonally silent likely underdiagnosed because do result endocrine syndrome. Tools used classify humans, particularly immunohistochemistry for lineage-specific transcription factors, useful canine feline unknown origin. Future studies required better understand full range pathology determine whether certain subtypes behave more aggressively than others. Currently, mechanisms underlie tumorigenesis largely unknown. understanding molecular background these could help identify improved pituitary-targeted therapeutics.